CoBi

Collective feeding in worms: Quantitative phenotyping and modelling identifies behavioral rules underlying aggregation in C. elegans

date
22.02.2018 
time
03:00 PM - 04:00 PM 
speaker
Linus Schumacher 
affiliation
Biological Physics, Imperial College London 
part of series
TUD ZIH Colloquium 
language
en 
main topic
Computer Science: general
subtopics
Biology: general
host
Ralph Müller-Pfefferkorn, Zentrum für Informationsdienste und Hochleistungsrechnen 
abstract

Collective behaviour is a hallmark of complex living systems. Often studied in groups of large animals or small cells, it less well understood at the mesoscopic scale. We investigate collective feeding of the nematode C. elegans, known for its easy genetic manipulation and stereotypic, yet complex behaviour. In this system, small genetic perturbations can lead to strikingly different population-level behaviours. We quantify behavioural differences between the „solitary“ lab strain and a „social“ aggregating mutant. To understand the mechanism of aggregation, we draw on concepts from motility-induced phase transitions and agent-based modelling. Finally, we investigate the potential benefits of collective feeding in an attempt to explain the predominance of aggregating strains in the wild.

 

Last update: 22.02.2018 07:39.

venue 

Andere (Willersbau A317) 


organizer 

Center for Information Services and High Performance Computing (TUD ZIH)
Zellescher Weg 12-14
01069 Dresden
telefon
+49 351 463-35450 
fax
+49 351 463-37773 
e-mail
Center for Information Services and High Performance Computing (TUD ZIH) 
homepage
http://tu-dresden.de/zih 
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