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UID:DSC-12422
DTSTART;TZID=Europe/Berlin:20170210T130000
SEQUENCE:1486713593
TRANSP:OPAQUE
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URL:https://dresden-science-calendar.de/calendar/de/detail/12422
LOCATION:TUD CRTD\, Fetscherstraße 10501307 Dresden
SUMMARY:Cramer: Genome transcription: mechanisms and regulation
CLASS:PUBLIC
DESCRIPTION:Speaker: Prof. Dr. Patrick Cramer\nInstitute of Speaker: Max Pl
 anck Institute for Biophysical Chemistry\, Department of Molecular Biology
 \, Göttingen\nTopics:\nBiologie\, Medizin\n Location:\n  Name: TUD CRTD (
 CRTD\, Auditorium left)\n  Street: Fetscherstraße 105\n  City: 01307 Dres
 den\n  Phone: +49 (0)351 458 82052\n  Fax: +49 (0)351 458 82059 \nDescript
 ion: Abstract: Our laboratory is combining structural biology with functio
 nal genomics and computational biology. Gene transcription is the first st
 ep in the expression of the genetic information and a focal point for cell
 ular regulation. Our goal is to understand the molecular mechanisms of gen
 e transcription and the principles of genomic regulation in eukaryotic cel
 ls. We use integrated structural biology and complementary functional stud
 ies to unravel the three-dimensional and functional architecture of large 
 macromolecular complexes involved in transcription. We also develop functi
 onal genomics methods and computational approaches to unravel the cellular
  mechanisms of genomic regulation. These efforts led to a first molecular 
 movie of transcription and provided insights into gene-regulatory cellular
  networks. Together\, these efforts shape the emerging fields of genome bi
 ology and molecular systems biology. Our aim is to understand the function
 al genome as a regulatory network based on the underlying structural and m
 olecular mechanisms. In my talk I will present the latest unpublished data
  from our efforts.
DTSTAMP:20260511T071635Z
CREATED:20170124T080512Z
LAST-MODIFIED:20170210T075953Z
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