CMCB Life Sciences Seminar: Dr. Ashley Seifert, University of Kentucky
- Datum
- 14.12.2023
- Zeit
- 13:00 - 14:00
- Serie
- CMCB Life Sciences Seminar
- Sprache
- en
- Hauptthema
- Willkommen
- Andere Themen
- Willkommen
- Beschreibung
Host: Tatiana Sandoval-Guzman
Title: "Unraveling the mechanistic basis for complex tissue regeneration in spiny mice"
Abstract: A mechanistic understanding for why mammals generally lack the ability to regenerate complex musculoskeletal tissue has remained a biological enigma for hundreds of years. The discovery that spiny mice (Acomys) can regenerate skin and musculoskeletal tissue has created an opportunity to discover key factors that stimulate a regenerative, rather than fibrotic, response to injury. Comparative analysis of regenerating spiny mice with non-regenerating rodents implicates macrophages and stress-activated MAPK proteins as key regulators of epimorphic regeneration in mammals. I will discuss ongoing studies from my lab exploring how these cellular and molecular components specifically drive a regenerative response or are instead involved in a more general wound healing response to injury.
- Links
Letztmalig verändert: 14.12.2023, 07:39:43
Veranstaltungsort
- Telefon
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- Bauing., Architektur
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