Convergence: Impacting Engineering Curricula, Patient Care & Implantable Microanalytical Systems

Datum

23.05.2024

Zeit

13:00 - 15:00

Sprecher

Anthony Guiseppi-Elie, Sc.D.

Zugehörigkeit

American International Institute of Medical Sciences, Engineering and Innovation, Anderson, SC 29621, USA

Serie

TUD nanoSeminar

Sprache

en

Hauptthema

Physik

Andere Themen

Physik

Host

Arezoo Dianat

Beschreibung

Progress toward and modeling of a minimally invasive penta-analyte biochip system, the Physiological Status Monitoring (PSM) BioChip™, designed for monitoring key biomarkers of physiological stress during hemorrhagic trauma and vascular allograft transplantation is presented. Intended to allow for patient stratification/segmentation, individual biomedical and biosensor elements employ nano-enabled Sensing, Measuring, and Actively Responding Technical (SMART) hydrogels that may be electroconductive and bioactive. In each case, molecular engineering of the ABIO-BIO (solid-to-soft) interface improves adhesion, analytical reproducibility, and functional device performance. These examples serve to showcase how convergence in research, particularly at C3B®, leads to the development of innovative solutions with applications in healthcare, biotechnology, and related fields. The collaborative efforts of researchers from diverse disciplines contribute to a more comprehensive and impactful approach to addressing complex challenges.
 1. Aggas, J. R. et al. Real-Time Monitoring Using Multiplexed Multi-Electrode Bioelectrical Impedance Spectroscopy for the Stratification of Vascularized Composite Allografts: A Perspective on Predictive Analytics. Bioengineering 10, 434 (2023).
 2. Abasi, S., Jain, A., Cooke, J. P. & Guiseppi-Elie, A. Electrically stimulated gene expression under exogenously applied electric fields. Frontiers in Molecular Biosciences 10, doi:10.3389/fmolb.2023.1161191 (2023).

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Letztmalig verändert: 24.05.2024, 07:40:03