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BEGIN:VEVENT
UID:DSC-20964
DTSTART;TZID=Europe/Berlin:20240704T150000
SEQUENCE:1720071608
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20240704T160000
URL:https://dresden-science-calendar.de/calendar/de/detail/20964
LOCATION:TUD Andreas-Schubert-Bau\, Zellescher Weg 1901069 Dresden
SUMMARY:Seminar: Microdosimetry of kidney cells exposed to 243Am and X-ray 
 irradiation (Pia Kahle)
CLASS:PUBLIC
DESCRIPTION:Speaker: \nInstitute of Speaker: \nTopics:\nPhysik\, Willkommen
 \n Location:\n  Name: TUD Andreas-Schubert-Bau (E19)\n  Street: Zellescher
  Weg 19\n  City: 01069 Dresden\n  Phone: \n  Fax: \nDescription: <p>In vit
 ro experiments with rat kidney cells (NRK-52E) exposed to 243 Am in cell c
 ulture medium show a decreasing cell viability with increasing americium c
 oncentration. Both the chemical cytotoxicity of americium and the dose cau
 sed by ionizing radiation have to be considered as possible causes. To det
 ermine the dose rate\, the influence of α-\, β- and γ- radiation was ex
 amined intra- and extracellularly in a detailed microdosimetric model. In 
 the in vitro experiments\, the dose rate is essentially caused by extracel
 lular α-radiation. At the americium concentrations used\, dose rates up t
 o the Gy/h range were achieved. Noteworthy the geometry of the cells is a 
 crucial parameter. In addition\, reference samples of untreated kidney cel
 ls were exposed to analog doses in an X-ray field. The cell viability curv
 es depending on the dose show good agreement for both approaches. In this 
 presentation\, both the microdosimetric calculations and the experimental 
 cell irradiation possibilities at the Institute for Nuclear and Particle P
 hysics will be presented.</p>
DTSTAMP:20260608T223438Z
CREATED:20240525T053858Z
LAST-MODIFIED:20240704T054008Z
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