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UID:DSC-22612
DTSTART;TZID=Europe/Berlin:20260518T153000
SEQUENCE:1779082570
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20260518T163000
URL:https://dresden-science-calendar.de/calendar/de/detail/22612
LOCATION:MPI-PKS\, Nöthnitzer Straße 3801187 Dresden
SUMMARY:Khammash: Perfect Adaptation in Biological Networks
CLASS:PUBLIC
DESCRIPTION:Speaker: Prof Mustafa Khammash\nInstitute of Speaker: ETH Züri
 ch\nTopics:\nPhysik\n Location:\n  Name: MPI-PKS ()\n  Street: Nöthnitzer
  Straße 38\n  City: 01187 Dresden\n  Phone: + 49 (0)351 871 0\n  Fax: \nD
 escription: A distinctive feature of many biological systems is their abil
 ity to adapt to persistent stimuli or disturbances that would otherwise dr
 ive them away from a desirable steady state. This resulting stasis enables
  reliable function across a wide range of external environments. We focus 
 on a stringent form of this behavior—robust perfect adaptation (RPA)—w
 hich remains resilient to certain network and parameter perturbations. As 
 in engineered control systems\, RPA is not incidental: it requires the reg
 ulating network to satisfy specific\, unavoidable structural constraints. 
 Using examples from systems biology and synthetic biology\, we show how th
 ese constraints arise in natural and engineered circuits. We argue that id
 entifying the structural basis of RPA allows us to move beyond implementat
 ion details and provides a principled lens for understanding regulatory co
 mplexity and information processing in biological systems
DTSTAMP:20260616T212915Z
CREATED:20260124T063608Z
LAST-MODIFIED:20260518T053610Z
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