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UID:DSC-22996
DTSTART;TZID=Europe/Berlin:20260924T110000
SEQUENCE:1790228265
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20260924T120000
URL:https://dresden-science-calendar.de/calendar/de/detail/22996
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Torres-Padilla: Epigenetic mechanisms of cellular plasticity
CLASS:PUBLIC
DESCRIPTION:Speaker: Maria Elena Torres-Padilla\nInstitute of Speaker: Helm
 holtz Zentrum München\, Germany\nTopics:\n\n Location:\n  Name: MPI-CBG (
 MPI-CBG CBG Large Auditorium)\n  Street: Pfotenhauerstraße 108\n  City: 0
 1307 Dresden\n  Phone: +49 351 210-0\n  Fax: +49 351 210-2000\nDescription
 : Research in our lab focuses on understanding how cells in the early embr
 yo integrate genetic and epigenetic information to initiate and orchestrat
 e a new developmental programme. After fertilisation of the oocyte by the 
 sperm\, the resulting zygote acquires the unique capacity to form a comple
 te new organism. This is a universal principle across species and is funda
 mental for the preservation of species and for multicellularity.  At these
  early developmental stages\, genetic\, epigenetic and mechanical mechanis
 ms are in place. Yet\, how these regulatory layers are integrated at the m
 olecular level remains still a poorly understood\, yet exciting area of re
 search. I will present our work investigating how the pervasive presence o
 f transposable elements in mammalian genomes\, chromatin function\, and ge
 nome nuclear organisation are integrated with nuclear mechanics to shape a
 nd regulate early developmental programmes. I will also illustrate how we 
 leverage these findings to restore cellular plasticity for reprogramming c
 ell fates.
DTSTAMP:20261011T140309Z
CREATED:20260618T054002Z
LAST-MODIFIED:20260924T053745Z
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