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UID:DSC-3952
DTSTART;TZID=Europe/Berlin:20121018T143000
SEQUENCE:1349800865
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20121018T153000
URL:https://dresden-science-calendar.de/calendar/de/detail/3952
LOCATION:Institut für Medizinische Informatik und Biometrie (IMB)\, Blasew
 itzer Straße 8601307 Dresden
SUMMARY:Kurth: Cancer Stem Cells in Development of Novel Predictive Biomark
 ers for Radiotherapy
CLASS:PUBLIC
DESCRIPTION:Speaker: Dr. Ina Kurth\nInstitute of Speaker: Oncoray\, Medical
  Faculty Carl Gustav Carus TU Dresden\nTopics:\nBiologie\, Medizin\n Locat
 ion:\n  Name: Institut für Medizinische Informatik und Biometrie (IMB) (3
 rd floor\, room 3.465)\n  Street: Blasewitzer Straße 86\n  City: 01307 Dr
 esden\n  Phone: \n  Fax: \nDescription: The success of radiotherapy being 
 the backbone approach of cancer treatment is often   impeded by tumor radi
 oresistance. Recent evidences suggest a small cell population   called can
 cer stem cells (CSC)\, which is resistant to conventional therapy includin
 g   radiotherapy leading to tumor recurrence.    Our data suggest a combin
 ation of cancer stem cell markers for identification of radioresistant  ce
 ll population. Irradiation of cancer cells increased the progenitor popula
 tion that can be   defined by classical stem cell markers including ALDH a
 ctivity\, CXCR4\, CD133\, ABCG2\, and   led to activation of PI3K/AKT and 
 epithelial-mesenchymal transition (EMT) signaling pathways.    Further aim
 ed studies will explore the role of cancer progenitors in development of  
  radioresistance and examine the predictive value of cancer stem cell mark
 ers on tumors   radiocurability.  
DTSTAMP:20260831T140118Z
CREATED:20121009T164105Z
LAST-MODIFIED:20121009T164105Z
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