Bi

Transient dynamics of membrane nanodomains in intact cells

Date
Dec 16, 2016
Time
11:00 AM - 12:00 PM
Speaker
Arnd Pralle
Affiliation
Dept. of Physics, University at Buffalo, The State University of New York, USA
Series
MPI-CBG Thursday Seminar
Language
en
Main Topic
Biologie
Other Topics
Biologie
Host
Alf Honigmann
Description
The dynamics of plasma membrane organization are notoriously difficult to study. We present a novel fluorescence spectroscopy approach that enables continuous analysis of the interaction membrane proteins with sub-microscopic clusters or the membrane cytoskeleton in intact cells. It quantifies the diffusion speed of proteins in live cell membranes and their strength of interaction with the cytoskeleton. Results from several applications will be presented including calcium dependent PIP2 modulation, influence of general anesthetics and membrane stiffness measurements.

Last modified: Dec 17, 2016, 8:42:00 AM

Location

Max Planck Institute of Molecular Cell Biology and Genetics (Auditorium (small half))Pfotenhauerstraße10801307Dresden
Phone
+49 351 210-0
Fax
+49 351 210-2000
E-Mail
MPI-CBG
Homepage
http://www.mpi-cbg.de

Organizer

Max Planck Institute of Molecular Cell Biology and GeneticsPfotenhauerstraße10801307Dresden
Phone
+49 351 210-0
Fax
+49 351 210-2000
E-Mail
MPI-CBG
Homepage
http://www.mpi-cbg.de
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