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UID:DSC-12338
DTSTART;TZID=Europe/Berlin:20170113T110000
SEQUENCE:1484294040
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20170113T120000
URL:https://dresden-science-calendar.de/calendar/en/detail/12338
LOCATION:TUD CRTD\, Fetscherstraße 10501307 Dresden
SUMMARY:Leptin: Cell shape and morphogenesis: sub-cellular and supra-cellul
 ar mechanisms
CLASS:PUBLIC
DESCRIPTION:Speaker: Maria Leptin\nInstitute of Speaker: EMBO Director & Pr
 ofessor at the Institute of Genetics University of Cologne\nTopics:\nBiolo
 gie\, Medizin\n Location:\n  Name: TUD CRTD (CRTD\, auditorium left)\n  St
 reet: Fetscherstraße 105\n  City: 01307 Dresden\n  Phone: +49 (0)351 458 
 82052\n  Fax: +49 (0)351 458 82059 \nDescription: Abstract:Maria Leptin ha
 s made contributions to several fields\, ranging from innate and adaptive 
 immunity to developmental genetics and cell biology. She is best known for
  her studies of what is considered the most profound embryonic process: ga
 strulation. Leptin discovered the essential players that regulate shape ch
 anges during gastrulation and elucidated their mechanism of action. Using 
 genetics\, biochemistry and cell biology\, she established the full regula
 tory cascade from a critical transcription factor during gastrulation to i
 ts target effector genes. Her current interest is to understand the physic
 al basis of the coordination of morphogenetic activities throughout the en
 tire organismPublications:Leptin\, M. and B. Grunewald. (1990).Cell shape 
 changes during gastrulation in Drosophila.Development 110\, 73-84.Leptin\,
  M. (1991)twist and snail as positive and negative regulators during Droso
 phila mesoderm development.Genes and Development 5\, 1568-1576Barrett\, K.
 \, Leptin\, M. and Settleman\, J (1997)The Rho GTPase and a putative RhoGE
 F mediate a signaling pathway for the cell shape changes in Drosophila gas
 trulationCell 91\, 905-915Seher\, T. and Leptin\, M. (2000)Tribbles\, a ce
 ll cycle brake that coordinates proliferation and morphogenesis during Dro
 sophila gastrulationCurrent Biology 10\, 623-629Kölsch V\, Seher T\, Fern
 andez-Ballester GJ\, Serrano L\, Leptin M. (2007)Control of Drosophila gas
 trulation by apical localization of adherens junctions and RhoGEF2.Science
  315\, 384-6.Stein C\, Caccamo M\, Laird G\, Leptin M. (2007)Conservation 
 and divergence of gene families encoding components of innate immune respo
 nse systems in zebrafish.Genome Biol. 8: R251.1 – 251.23Rembold M\, Cigl
 ar L\, Yáñez-Cuna JO\, Zinzen RP\, Girardot C\, Jain A\, Welte MA\, Star
 k A\, Leptin M\, Furlong EE. (2014)A conserved role for Snail as a potenti
 ator of active transcription.Genes Dev. 28:167-81.Gilmour\, D.\, Rembold\,
  M.\, and Leptin\, M. (2017)From Morphogen To Morphogenesis and BackNature
  (in press).
DTSTAMP:20260703T093111Z
CREATED:20170104T074831Z
LAST-MODIFIED:20170113T075400Z
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