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UID:DSC-12439
DTSTART;TZID=Europe/Berlin:20170215T093000
SEQUENCE:1487230860
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20170215T103000
URL:https://dresden-science-calendar.de/calendar/en/detail/12439
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Witte: Biomolecular Interaction Analytics using MicroScale Thermoph
 oresis – A Hands-On Review
CLASS:PUBLIC
DESCRIPTION:Speaker: David Witte\nInstitute of Speaker: NanoTemper Technolo
 gies GmbH\nTopics:\nBiologie\n Location:\n  Name: MPI-CBG (Seminar Room 1s
 t floor)\n  Street: Pfotenhauerstraße 108\n  City: 01307 Dresden\n  Phone
 : +49 351 210-0\n  Fax: +49 351 210-2000\nDescription: The analysis of bio
 molecular interactions\, such as protein-protein\, protein-nucleic acid or
  protein-small molecule\, is a prerequisite to understand biological proce
 sses on a molecular level. In the recent years MicroScale Thermophoresis (
 MST) has proven to be a fast and efficient tool for the quantification of 
 biomolecular interactions. As MST yields important information about sampl
 e quality such as aggregation in addition to the dissociation constant\, t
 his method allows for a straight forward optimization of sample conditions
 . In order to get the maximum out of an MST experiment\, it is necessary r
 ead the signs of different events and artifacts. This presentation focuses
  on the practical aspects of MST such as experimental design\, data evalua
 tion and assay optimization. In detail subjects like non-standard binding 
 events\, alternative labeling strategies and fluorescence effects will be 
 discussed.
DTSTAMP:20261006T170439Z
CREATED:20170126T073737Z
LAST-MODIFIED:20170216T074100Z
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