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UID:DSC-15461
DTSTART;TZID=Europe/Berlin:20190131T160000
SEQUENCE:1548893312
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20190131T170000
URL:https://dresden-science-calendar.de/calendar/en/detail/15461
LOCATION:TUD CRTD\, Fetscherstraße 10501307 Dresden
SUMMARY:Götz: Novel mechanisms of neurogenesis and neuronal repair
CLASS:PUBLIC
DESCRIPTION:Speaker: Prof. Magdalena Götz\nInstitute of Speaker: Institute
  for Stem Cell Research\, Helmholtz Center Munich and Biomedical Center\, 
 University of Munich\, Germany\nTopics:\nBiologie\, Medizin\n Location:\n 
  Name: TUD CRTD (CRTD\, auditorium left)\n  Street: Fetscherstraße 105\n 
  City: 01307 Dresden\n  Phone: +49 (0)351 458 82052\n  Fax: +49 (0)351 458
  82059 \nDescription: AbstractWe study the mechanisms of neurogenesis in o
 rder to implement them for neuronal repair. I will present unpublished wor
 k about novel molecular mechanisms important for neurogenesis in the devel
 oping murine cerebral cortex and will then turn to using these for direct 
 neuronal reprogramming after traumatic injury of the adult murine cerebral
  cortex in vivo. I will discuss different viral vector approaches and up-d
 ate on a recent breakthrough in direct glia-to-neuron reprogramming achiev
 ing high efficiency and mature neuronal subtypes sending out long range pr
 ojections. I will close by discussing the integration of replaced neurons 
 into the circuitry of the adult murine cerebral cortex\, that normally doe
 s not integrate new neurons at adult stages and present unpublished data a
 bout the mechanisms regulating this integration. Taken together\, our know
 ledge about basic mechanisms of neurogenesis allowed making great strides 
 towards neuronal repair. 5 most recent papersMalatesta et al.\, 2000Heins 
 et al.\, 2002 Stahl et al.\, 2013 Sirko et al.\, 2013 Falkner\, Grade et a
 l.\, 2016
DTSTAMP:20260821T144631Z
CREATED:20181215T000859Z
LAST-MODIFIED:20190131T000832Z
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