CMCB Life Sciences Seminar: Jan Born, University of Tübingen
- Date
- Jan 26, 2023
- Time
- 1:00 PM - 2:00 PM
- Series
- CMCB Life Sciences Seminar
- Language
- en
- Main Topic
- Willkommen
- Other Topics
- Willkommen
- Description
Host: Henrik Bringmann (BIOTEC)
Title: “Sleep – a brain state serving memory”
Abstract:
Whereas memories are optimally encoded and retrieved when the brain is awake, the consolidation and formation of long-term memory requires an offline mode of processing as optimally established only during sleep. Based on evidence from behavioral and neurobiological studies in humans and rodents, I will consider the formation of long-term memory during sleep as an “active systems consolidation” process in which the repeated neuronal replay of memory representations originating from the hippocampus during slow-wave sleep (SWS) leads to a gradual transformation and integration of representations into extrahippocampal, mainly neocortical networks. I will highlight three features of this process: (i) Hippocampal replay that, by capturing episodic memory aspects, drives consolidation of representations residing inside and outside the hippocampus; (ii) brain oscillations hallmarking SWS and rapid-eye movement (REM) sleep, respectively, which provide mechanisms to regulate both information flow across distant brain networks and local synaptic plasticity; and (iii) qualitative transformations of memories during sleep-dependent systems consolidation resulting in abstract schema-like representations.- Links
Last modified: Jan 26, 2023, 7:38:52 AM
Location
- Phone
- +49 (0)351 458 82052
- Fax
- +49 (0)351 458 82059
- TUD CRTD
- Homepage
- https://tu-dresden.de/cmcb/crtd
Organizer
- Phone
- +49 351 463-40359
- Fax
- +49 351 463-40322
- TUD CMCB
- Homepage
- https://tu-dresden.de/cmcb
- Biology
- Chemistry
- Civil Eng., Architecture
- Computer Science
- Economics
- Electrical and Computer Eng.
- Environmental Sciences
- for Pupils
- Law
- Linguistics, Literature and Culture
- Materials
- Mathematics
- Mechanical Engineering
- Medicine
- Physics
- Psychology
- Society, Philosophy, Education
- Spin-off/Transfer
- Traffic
- Training
- Welcome