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UID:DSC-21101
DTSTART;TZID=Europe/Berlin:20240704T130000
SEQUENCE:1720071605
TRANSP:OPAQUE
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URL:https://dresden-science-calendar.de/calendar/en/detail/21101
LOCATION:TUD Materials Science - HAL\, Hallwachsstraße 301069 Dresden
SUMMARY:Gao: Electronic Nano-biosensors Based on Graphene Transistors
CLASS:PUBLIC
DESCRIPTION:Speaker: Zhaoli Gao\nInstitute of Speaker: Chinese University o
 f Hong Kong\nTopics:\nPhysik\n Location:\n  Name: TUD Materials Science - 
 HAL (HAL Bürogebäude - 115)\n  Street: Hallwachsstraße 3\n  City: 01069
  Dresden\n  Phone: \n  Fax: \nDescription: Probing biosystems with two-dim
 ensional (2D) materials provides tremendous opportunities for highly sensi
 tive detection of physiological properties at the molecular level\, which 
 can pave the way toward early-stage disease diagnosis and improved healthc
 are outcomes. In this talk\, I will introduce the process we have develope
 d for scalable fabrication of 2D-biosensor arrays for multiplexed detectio
 n of disease biomarkers\, where a graphene field effect transistor (GFET) 
 is utilized for signal transduction\, and a biomolecular layer\, e.g.\, pr
 otein\, nuclide acid\, serves as the biological recognition element. Furth
 er\, integrating the hybridization chain reaction (HCR) process with GFET 
 readout leads to oligonucleotide detection with sensitivity at the aM leve
 l. Looking to the future\, I will discuss the synthesis of crystalline mul
 tilayer graphene and transition metal dichalcogenide materials with band g
 aps\, providing a pathway toward next-generation biosensors with even grea
 ter sensitivity. Finally\, I will discuss the ongoing development of a uni
 versal sensing platform based on aptamer-GFET biosensors that is potential
 ly useful for wearable electronics for detecting health and performance bi
 omarkers in sweat. Probing biosystems with two-dimensional (2D) materials 
 provides tremendous opportunities for highly sensitive detection of physio
 logical properties at the molecular level\, which can pave the way toward 
 early-stage disease diagnosis and improved healthcare outcomes. In this ta
 lk\, I will introduce the process we have developed for scalable fabricati
 on of 2D-biosensor arrays for multiplexed detection of disease biomarkers\
 , where a graphene field effect transistor (GFET) is utilized for signal t
 ransduction\, and a biomolecular layer\, e.g.\, protein\, nuclide acid\, s
 erves as the biological recognition element. Further\, integrating the hyb
 ridization chain reaction (HCR) process with GFET readout leads to oligonu
 cleotide detection with sensitivity at the aM level. Looking to the future
 \, I will discuss the synthesis of crystalline multilayer graphene and tra
 nsition metal dichalcogenide materials with band gaps\, providing a pathwa
 y toward next-generation biosensors with even greater sensitivity. Finally
 \, I will discuss the ongoing development of a universal sensing platform 
 based on aptamer-GFET biosensors that is potentially useful for wearable e
 lectronics for detecting health and performance biomarkers in sweat.
DTSTAMP:20260721T182232Z
CREATED:20240607T053755Z
LAST-MODIFIED:20240704T054005Z
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