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Phase transitions in confluent epithelia

Date
Dec 9, 2024
Time
4:30 PM - 5:30 PM
Speaker
Prof. Luca Giomi
Affiliation
Instituut-Lorentz for Theoretical Physics, Universiteit Leiden
Series
MPI-PKS Kolloquium
Language
en
Main Topic
Physik
Other Topics
Physik
Description
In spite of the absence of gaps and interstitial structures, confluent layers of epithelial cells are able to migrate collectively and remove excess cells by extrusion. While in common with foams and other passive confluent fluids, both these phenomena crucially rely on the active remodelling of the cellular network, via topological transformations known as T1 and T2 processes. Using a combination of active hydrodynamics and Renormalization Group methods, I will show that both collective migration and cell extrusion can be thought as continuum phase transitions, with the former being in the same universality class of the Kosterlitz-Thouless transition and the latter reminiscent of sublimation in solids.

Last modified: Nov 23, 2024, 7:38:00 AM

Location

Max-Planck-Institut für Physik komplexer SystemeNöthnitzer Straße3801187Dresden
Phone
+ 49 (0)351 871 0
E-Mail
MPI-PKS
Homepage
http://www.mpipks-dresden.mpg.de

Organizer

Max-Planck-Institut für Physik komplexer SystemeNöthnitzer Straße3801187Dresden
Phone
+ 49 (0)351 871 0
E-Mail
MPI-PKS
Homepage
http://www.mpipks-dresden.mpg.de
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