From Sense Though Missense to Nonsense: A Translational Lens on Mutation
- Date
- May 8, 2025
- Time
- 11:00 AM - 12:00 PM
- Speaker
- Zoya Ignatova
- Affiliation
- University of Hamburg
- Series
- MPI-CBG Thursday Seminar
- Language
- en
- Main Topic
- Biologie
- Host
- Agnes Toth-Petroczy
- Description
- Variations at sense codons can have wide-ranging effects on gene expression, protein function, and cellular health. This talk explores how single nucleotide changes transition codons from sense to missense and ultimately to nonsense, with a special focus on the role of translation dynamics in shaping the molecular consequences of genetic variations. By examining ribosome dynamics, codon context, and translational fidelity, we uncover how these mutations influence protein output and pathogenicity.
Last modified: May 8, 2025, 7:38:37 AM
Location
Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG CBG Large Auditorium)Pfotenhauerstraße10801307Dresden
- Phone
- +49 351 210-0
- Fax
- +49 351 210-2000
- MPI-CBG
- Homepage
- http://www.mpi-cbg.de
Organizer
Max Planck Institute of Molecular Cell Biology and GeneticsPfotenhauerstraße10801307Dresden
- Phone
- +49 351 210-0
- Fax
- +49 351 210-2000
- MPI-CBG
- Homepage
- http://www.mpi-cbg.de
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