Bi

Polarity regulators and trophoblast fusion- Expect the unexpected

Date
Sep 16, 2025
Time
11:00 AM - 12:15 PM
Speaker
Meghan Riddell
Affiliation
Depts of Obstetrics and Gynecology and Physiology, University of Alberta, Canada
Language
en
Main Topic
Biologie
Host
Claudia Gerri
Description
Villous trophoblast differentiation is critical for human placental morphogenesis. A key event in villous differentiation is the fusion of progenitor cytotrophoblasts to form a giant multinucleate syncytium, the syncytiotrophoblast. We have identified conserved and unique roles for the cell polarity proteins atypical protein kinase-c and ezrin in the regulation of cytotrophoblast fusion using human first trimester placental explants and organoids.

Last modified: Sep 16, 2025, 7:36:43 AM

Location

Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG CBG Galleria II (VC))Pfotenhauerstraße10801307Dresden
Phone
+49 351 210-0
Fax
+49 351 210-2000
E-Mail
MPI-CBG
Homepage
http://www.mpi-cbg.de

Organizer

Max Planck Institute of Molecular Cell Biology and GeneticsPfotenhauerstraße10801307Dresden
Phone
+49 351 210-0
Fax
+49 351 210-2000
E-Mail
MPI-CBG
Homepage
http://www.mpi-cbg.de
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