The presence of very small embryonic like stem cells (VSELs) in adult tissues and an emerging role of microvesicles, exosomes and paracrine signals in regenerative medicine – towards development of novel therapeutic approaches.

Date

May 3, 2013

Time

11:00 AM - 12:00 PM

Speaker

Prof. Mariusz Ratajczak, University of Louisville

Language

en

Main Topic

Willkommen

Other Topics

Willkommen

Description

Mariusz Z. Ratajczak, M.D., Ph.D, D.Sci d.hc is the Henry and Stella Hoenig Endowed Chair in Cancer Biology and the Director of the Stem Cell Institute at the University of Louisville's James Graham Brown Cancer Center. Dr. Ratajczak is an internationally known investigator in the field of adult stem cell biology. He has published numerous books and more than 400 peer reviewed publications and is a frequent speaker at conferences worldwide. For the past 25 years, he has worked to develop new concepts in hematopoietic transplantation biology. Studies include the development of novel strategies for the purging of hematopoietic transplants, protocols to accelerate platelet recovery after transplantation as well as novel strategies to enhance both mobilization and engraftment of hematopoietic stem cells. He pioneered studies into the role of innate immunity and complement cascade as a major modulator of the SDF-1-CXCR4 axis in the trafficking of stem cells, elucidated the molecular mechanisms responsible for metastasis of pediatric sarcomas to the bone marrow, and recently identified in adult bone marrow and cord blood a population of pluripotent very small embryonic-like stem cells (VSEL). These cells, drawn from adult bone marrow, appear to mimic the ability of stem cells to multiply and develop into other kinds of cells

Links

• to announcement of the organizer

Last modified: May 3, 2013, 9:42:06 AM